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| Single-Season Games Leaderboard | |
| * - Indicates Hall of Fame |
| Rank | Player | Games | PA | Year | Career Leaderboard |
| 1. | Vernon Wells | 163 | 682 | 2014 | |
| Junior Spivey | 163 | 746 | 2005 | ||
| Jorge Posada | 163 | 716 | 2005 | ||
| Adam Everett | 163 | 665 | 2005 | ||
| 5. | Hernan Leyba | 162 | 718 | 2022 | |
| Bill Sturm | 162 | 678 | 2022 | ||
| Silvano Chao | 162 | 648 | 2022 | ||
| Richard Keele | 162 | 751 | 2021 | ||
| Dan Kain | 162 | 704 | 2021 | ||
| Arthur Reavis | 162 | 670 | 2021 | ||
| Simon Espinosa | 162 | 668 | 2021 | ||
| Pedro Magana | 162 | 637 | 2021 | ||
| Richard Martines | 162 | 615 | 2021 | ||
| Wilfredo Contreras | 162 | 710 | 2020 | ||
| Bobby McClendon | 162 | 695 | 2020 | ||
| Ronald Gibson | 162 | 672 | 2020 | ||
| Robert Lenoir | 162 | 656 | 2020 | ||
| Daniel Ferretti | 162 | 638 | 2020 | ||
| Robert Castillo | 162 | 619 | 2020 | ||
| Thomas Mattingly | 162 | 703 | 2019 | ||
| Syo-Go Shinsaku | 162 | 642 | 2019 | ||
| Wilfredo Contreras | 162 | 630 | 2019 | ||
| Scott Castleberry | 162 | 628 | 2019 | ||
| Alvaro Baca | 162 | 768 | 2018 | ||
| Naofumi Doi | 162 | 740 | 2018 | ||
| Harry Dade | 162 | 728 | 2018 | ||
| Robert Adams | 162 | 702 | 2018 | ||
| Roland Bowes | 162 | 689 | 2018 | ||
| Warner Madrigal | 162 | 686 | 2018 | ||
| Ray Laymon | 162 | 600 | 2018 | ||
| David Zalewski | 162 | 750 | 2017 | ||
| Francisco Solis | 162 | 660 | 2017 | ||
| Robert Schmidt | 162 | 716 | 2016 | ||
| Jack Cust | 162 | 694 | 2016 | ||
| Edward Bohanan | 162 | 676 | 2016 | ||
| Matthew Flick | 162 | 675 | 2016 | ||
| Jacky Hernandez | 162 | 657 | 2016 | ||
| Edward Bohanan | 162 | 739 | 2015 | ||
| Dioner Navarro | 162 | 721 | 2015 | ||
| David Zalewski | 162 | 718 | 2015 | ||
| J.R. House | 162 | 675 | 2015 | ||
| Dave Krynzel | 162 | 713 | 2013 | ||
| William Maldanado | 162 | 708 | 2013 | ||
| Gabriel Pantoja | 162 | 684 | 2013 | ||
| Brent Clevlen | 162 | 671 | 2013 | ||
| Prince Fielder | 162 | 669 | 2013 | ||
| Kevin Alcazar | 162 | 702 | 2012 | ||
| Prince Fielder | 162 | 655 | 2012 | ||
| Andy Gonzalez | 162 | 633 | 2012 | ||
| Orlando Hudson | 162 | 728 | 2011 | ||
| Jeremy Hermida | 162 | 716 | 2011 | ||
| Gabriel Pantoja | 162 | 693 | 2011 | ||
| Vernon Wells | 162 | 689 | 2011 | ||
| Michael McClellan | 162 | 619 | 2011 | ||
| Kevin Cash | 162 | 659 | 2010 | ||
| Lance Niekro | 162 | 628 | 2010 | ||
| Troy Glaus | 162 | 587 | 2010 | ||
| Todd Helton | 162 | 723 | 2009 | ||
| Robby Hammock | 162 | 664 | 2009 | ||
| Chris Fallon | 162 | 645 | 2009 | ||
| David Ortiz | 162 | 691 | 2008 | ||
| Robby Hammock | 162 | 666 | 2008 | ||
| Michael Young | 162 | 746 | 2007 | ||
| Richie Sexson | 162 | 716 | 2007 | ||
| Jason Phillips | 162 | 704 | 2007 | ||
| Magglio Ordonez | 162 | 691 | 2007 | ||
| Corey Patterson | 162 | 689 | 2007 | ||
| Bill Mueller | 162 | 640 | 2007 | ||
| Jose Bautista | 162 | 606 | 2007 | ||
| Richie Sexson | 162 | 700 | 2006 | ||
| Ronnie Belliard | 162 | 654 | 2006 | ||
| Richie Sexson | 162 | 723 | 2005 | ||
| Jeff Kent | 162 | 701 | 2005 | ||
| Cristian Guzman | 162 | 695 | 2005 | ||
| Dmitri Young | 162 | 677 | 2005 | ||
| Eric Hinske | 162 | 611 | 2005 | ||
| Chris Woodward | 162 | 547 | 2005 | ||
| Nomar Garciaparra | 162 | 743 | 2004 | ||
| Jose Valentin | 162 | 701 | 2004 | ||
| Corey Koskie | 162 | 680 | 2004 | ||
| Joe Crede | 162 | 641 | 2004 | ||
| 82. | Herman Hofer | 161 | 664 | 2021 | |
| Larry Deacon | 161 | 654 | 2020 | ||
| Grady Sizemore | 161 | 623 | 2019 | ||
| Herman Hofer | 161 | 688 | 2018 | ||
| James Lucero | 161 | 734 | 2017 | ||
| William Horner | 161 | 637 | 2015 | ||
| Gabriel Pantoja | 161 | 680 | 2014 | ||
| Brendan Harris | 161 | 675 | 2013 | ||
| Austin Kearns | 161 | 651 | 2011 | ||
| Andy Gonzalez | 161 | 570 | 2011 | ||
| Gabriel Pantoja | 161 | 698 | 2010 | ||
| Josh McKinley | 161 | 668 | 2010 | ||
| Jimmy Rollins | 161 | 720 | 2004 | ||
| Jim Thome | 161 | 691 | 2004 | ||
| Neifi Perez | 161 | 647 | 2004 | ||
| 97. | Dan Kain | 160 | 680 | 2022 | |
| Howard Wilson | 160 | 649 | 2021 | ||
| Zoilo Ruiz | 160 | 635 | 2021 | ||
| Kevin Johnson | 160 | 584 | 2020 |
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